Listofcontributors,vii
Preface,ix
Acknowledgements,x
1Haemophilia:molecularbiologyatthecentreof
humandisease,1
E.G.D.Tuddenham
2DNA.RNAandproteins,24
J.Sinclair
3Analysinghumangenes,40
J.Sinclair
4Transcriptionalcontrolofhumangene
expression,60
W.B.Solomon
5Principlesofmedicalgenetics,77
J.M.Connor
6Monogenicdisorders,95
S.J.KenwrickandT.M.Cox
7Polygenicdisorders,129
J.Scott
8Molecularbiologyofcancer,149
M.J.C.EllisandK.Sikora
9Inheritedcancers,172
B.A.JLPonder
Molecularbiologyoftheimmuneresponse,191
D.B.G.Oliveira,T.H.RabbittsandA.Carmichael
Humanautoimmunity,202
A.P.WeetmanandD.B.Oliveira
Microbialinfections,222
R.C.Matthews,J.M.HopkinandJ.Burnie
Viralinfections,240
L.K.BorysiewiczandJ.G.P.Sissons
Recombinantproductsformedicaluse,260
T.C.PeakmanandM.J.Page
Drugdiscovery,271
G.Darby
Genetherapy,284
A.M.L.Lever
Prenataldiagnosis,299
P.M.HurleyandCH.Rodeck
Molecularbiologyandthefutureofmedicine,311
T.M.Cox
Glossary,323
Index,329
Colourplatesfallbetweenpp.214and215