Contributing Authors
Preface
PART 1.FUNDAMENTALS OF NEUROPHARMACOLOGY
1.BASIC PRINCIPLES OF NEUPOPHARMACOLOGY
How Drugs work
Drugs As Tools to Probe Brain Function
Drug Bingding
Drug Efficacy
Dose-Dependent Drug Reponse
Drug Interaction With Noreceptor Proteins
Neuropharmacology in the Molecular Era Molecular Diversity of the Brain
2.NEURONS AND GLIA
The Neuron
The Cell Body
The Axon
Dendrites
The cytoskeleton and the Transport of Proteins
The Synapse
Glia
Astrocytes
Oligodendrocytes and Schwann Cells
Microglia
Cerebral Blood flow
Blood-Brain Barrier
3.ELECTORICAL EXCITABILTY OF NEURONS
4.SYNAPTIC TRANSMISSION
5.SIGNAL TRANSDUCTION PATHWAYS IN THE BRAIN
6.SIGNALING TO THE NUCLEUS
PART 2.NEURAL SUBSTRATES OF DRUG ACIDS
7.EXCITATORY AND INHIBITORY AMINO ACLDS
8.CATECHOLAMINES
9.SEROTONIN,ACETYLCHOLINE,AND HISTAMINE
10.NEUROPEPTIDES AND PURINES
11.NEUROTROPHIC FACTORS
NPART 3.NEUROPHARMACOLOGY OF SPECIFIC NEURAL FUNCITIONS AND RELATED DISORDERS
12.AUTONOMIC NERVOUS SYSTEM
13.NEUROENDOCRINE CONTROL OF THE INTERNAL MILIEU
Index