Preface
Acknowledgements
Dedication
PartⅠ:Development,Structure,andFunction
1.OverviewoftheNervousSystem
Introduction
Overalldevelopmentofthenervoussystem
2.CellularPhysiologyoftheNervousSystem
Neuronalstructureandvariation
Thecentralnervoussystemenvironment
Synaptictransmission
Excitationandinhibition
Damageandrepairinthenervoussystem
3.TheSomatosensorySystem
Thespinalcordandspinaltracts
Somatosensationandthesensorycortex
Nociceptionandtheperceptionofpain
4.MotorControl
Movementcontrol
Motorunitsandrecruitmentofmusclefibres
Reflexactionandmuscletone
Themotorcortexandpyramidaltracts
Basalgangliaandthalamus
Thecerebellum
Thevestibularsystem,posture,andlocomotion
5.TheBrainstem
Thebrainstemnuclei
Thereticularformation
Brainstem-actingdrugsandgeneralanaesthetics
6.TheAutonomicNervousSystem
Introduction
Structureandfunctionofthesympatheticnervoussystem
Structureandfunctionoftheparasympatheticnervoussystem
Theentericnervoussystem
7.Vision
Theeye
Retinalfunctionandimageprocessing
Centralvisualpathwaysandthevisualcortex
Attentionandperception
8.Hearing
Theearandconductionofsound
Thecentralauditorypathwaysandtheauditorycortex
9.OlfactionandTaste
Receptionsfortasteandsmell
Centralpathwaysoftasteandsmell
10.HigherCentresoftheCentralNervousSystem
Localizationofbrainfunctionandbehaviour
Learningandmemory
Thelimbicsystem
Cognitivedevelopmentanddegeneration
Pharmacologyofhighercentralnervoussystemfunction
PartⅡ:ClinicalAssessment
11.TakingaHistory
Thingstorememberwhentakingahistory
Thestructureofthehistory
Commonpresentingcomplaints
12.TheNeurologicalExamination
Speech
Mentalstateandhigherfunctions
Gait
Thecranialnerves
Themotorsystem
Sensation
Theautonomicnervoussystem
Examinationoftheunconsciouspatien
13.FurtherInvestigations
Neurophysiologicalinvestigations
Routineinvestigations
Imagingofthenervoussystem
PartⅢ:BasicPathology
14.TheCentralNervousSystem
Commonpathologicalfeaturesofthecentralnervoussystem
Malformations,developmentaldisease,andperinatalinjury
Traumaofthecentralnervoussystem
Cerebrovasculardisease
Infectionsofthecentralnervoussystem
Demyelinationanddegeneration
Metabolicdisordersandtoxins
Neoplasmsofthecentralnervoussystem
Epilepsy
Diseasesoftheautonomicnervoussystem
15.PathologyofthePeripheralNervesandMuscle
Hereditaryneuropathies
Traumaticneuropathies
Inflammatoryneuropathies
Infectiousneuropathies
Metobolicandtoxicneuropathies
Neurocutaneoussyndromes
Diseasesofthemuscleandneuromuscularjunction
PartⅣ:Self-assessment
Multiple-choiceQuestions
Short-answerQuestions
EssayQuestions
MCQAnswers
SAQAnswers
Appendices
Appendix1:grossanatomy
Appendix2:vascularsupplytothecentralnervoussystem
Index