基因的表达与调控（英文版）

定　价：¥128.00

作　者：	马骏
出版社：	高等教育出版社
丛编项：
标　签：	生物

购买这本书可以去

ISBN：	9787040176759	出版时间：	2006-12-01	包装：	精装
开本：	16开	页数：	582	字数：

内容简介

　　This book offers a comprehensive look into the science ofgene expression and regulation. Focusing on topics such asactions of nuclear receptors， RNA processing， and DNAmethylation and imprinting， Gene Expression andRegulation is edited by a leading biologist and includescontributions by experts in the field.

作者简介

　　Jun Ma is an Associate Professor at the Division of Developmental Biology， Cincinnati Childrens Hospital Research Foundation and University of Cincinnati College of Medicine. He graduated from Peking University in 1982， majoring in Biology. He did his graduate work with Mark Ptashne at the Department of Biochemistry and Molecular Biology in Harvard University， and was a Junior Fellow at the Harvard Society of Fellows between 1989-1992.　He spent the summer of 1988 in the laboratory of Christiane N/isslein-Volhard at the Max-Planck- Institute for Developmental Biology in T/ibingen to collaborate with Wolfgang Driever. He joined the faculty of the University of Cincinnati College of Medicine in 1992 and has remained there since.　Currently he also has a collaborative base at the Institute of Biophysics of the Chinese Academy of Sciences in Beijing.　His earlier work on the yeast activator GAL4 helped pave the way to the development of the yeast two-hybrid system.　His current　research focuses on the mechanisms of transcription control and development in Drosophila.

图书目录

About the Editor
Preface
Section Ⅰ The History
Chapter 01　Transcription: The Never Ending Story
Section Ⅱ The Machinery
Chapter 02　The General Transcription Machinery and Preinitiation Complex Formation
Chapter 03　The Dynamic Association of RNA Polymerase II with Initiation. Elongation, and RNA Processing Factors during the Transcription Cycle
Chapter 04　General Cofactors: TFIID, Mediator and USA
Chapter 05　Chromatin and Regulation of Gene Expression
Chapter 06 HATs and HDACs　111
Chapter 07　Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription
Section Ⅲ The Regulators
Chapter 08　Transcriptional Activators and Activation Mechanisms
Chapter 09　Transcriptional Repressors and Repression Mechanisms
Chapter 10　STATs in Cytokine-mediated Transcriptional Regulation
Chapter 11　Transcriptional Regulation by Smads
Chapter 12　The Rb and E2F Families of Proteins
Chapter 13　c-Jun: A Complex Tale of a Simple Transcription Factor
Chapter 14　HIV Tat and the Control of Transcriptional Elongation
Chapter 15　Post-translational Modifications of the p53 Transcription Factor
Chapter 16　Actions of Nuclear Receptors
Chapter 17　NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators
Chapter 18　Hox Genes
Chapter 19　Nuclear Factor-kappa B
Chapter 20　The ATF Transcription Factors in Cellular Adaptive Responses
Section Ⅳ The Genome
Chapter 21　Function and Mechanism of Chromatin Boundaries
Chapter 22　Heterochromatin and X Inactivation
Chapter 23　DNA Methylation Regulates Genomic Imprinting, X Inactivation, and Gene Expression during Mammalian Development
Chapter 24　Comparative Genomics of Tissue Specific Gene Expression
Chapter 25　Transcription and Genomic Integrity
Chapter 26　Cell Death and Transcription
Section Ⅴ Special Topics
　Chapter 27 Pre-mRNA Splicing in Eukaryotic Cells
　Chapter 28 Genome Organization: The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation
　Chapter 29 The Biogenesis and Function of MicroRNAs
　Chapter 30 Transcription Factor Dynamics
　Chapter 31 Actin, Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control
　Chapter 32 Wnt Signaling and Transcriptional Regulation
　Chapter 33 Regulatory Mechanisms for Floral Organ Identity Specification inArabidopsis thaliana
　Chapter 34 Transcription Control in Bacteria
　Chapter 35 Gene Therapy: Back to the Basics