1 Concepts, Challenges and Perspectives in Cancer Research
1.1 Cancer is a Well-Organized Tissue, Constructing a Specified Cancer Microenvironment
1.1.1 Cancer Associated Stromal Cells
1.1.2 Extracellular Matrix in Tumor
1.I.3 Tumor Acidic Microenvironment
1.2 lleterogeneity of Cancer Cell Population and Cancer Stem Cell Hypothesis
1.2.1 Cancer Stem Cell ttypothesis
1.2.2 Arguments against Cancer Stem Cell Hypothesis
1.3 Cancer is a Systems Disease-- A Disease of Systems Dysregulation, Characterized by Abnormal Growth of the Defmed Tissue or Organ
1.3.1 Systemic Regulatory Systems to Control the Host-Cell Homeostasis
1.4 Prospects and Implications
References
2 Systemic Dysregulation in the Development of Hepatocellular Carcinoma
3 Genomics of Hepatocellular Carcinoma
4 Biornarkers of Hepatocellular Carcinoma,
5 Metabonomics of Hepatocellular Carcinoma
6 Signal Transduction of Hepatocellular Carcinoma
7 Cancer Stem Cells of Hepatocellular Carcinoma
8 Immunology of Liver
9 Immunosuppresssioa and Immune Escape in Liver Cancer.
10 Immunotherapy of Hepatocellular Carcinoma
11 Chemoprevention of Hepatic Cancer in Aflatoxin Endemic Areas
12 Metastasis of Hepatic Cancer
13 Integrated Treatment of Hepatic Cancer
14 Liver Transplantation for HepatoceUular Carcinoma
Index