Williams血液学（第9版 英文版）

简 目ContributorsPreface PART IClinical Evaluationof the PatientPARTII TheOrganization of the LymphohematopoieticTissuesPARTIII EpochalHematologyPARTIV Molecular and CellularHematologyPARTV TherapeuticPrinciplesPARTVI The ErythrocytePARTVII Neutrophils,Eosinophils,Basophils, and MastCellsPARTVIII Monocytes and MacrophagesPARTIX Lymphocytes and Plasma CellsPARTX MalignantMyeloid DiseasesPARTXI MalignantLymphoid DiseasesPARTXII Hemostasis andThrombosisPARTXIII Transfusion MedicineIndex v 目 录Contributors. . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. .ixPreface. . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . .xxi PART IClinicalEvaluation of the Patient1.InitialApproachto the Patient:HistoryandPhysicalExamination2.Examinationof Blood Cells3.ExaminationofTheMarrow4.ConsultativeHematologyPART IITheOrganization of the LymphohematopoieticTissues5.Structureof the Marrowand the HematopoieticMicroenvironment6.The Organizationand StructureofLymphoidTissuesPART IIIEpochal Hematology7.Hematologyof the FetusandNewborn8.HematologyduringPregnancy9.Hematology in OlderPersons PART IVMolecular and CellularHematology10.Genetic PrinciplesandMolecular Biology11.Genomics12.Epigenetics13.Cytogeneticsand Genetic Abnormalities14.MetabolismofHematologicNeoplastic Cells15.ApoptosisMechanisms:Relevanceto the HematopoieticSystem16.Cell-CycleRegulationandHematologicDisorders17.SignalTransductionPathways18.HematopoieticStem Cells, Progenitors,andCytokines19.TheInflammatoryResponse20.InnateImmunity21.Dendritic Cells andAdaptiveImmunityPARTVTherapeuticPrinciples22.PharmacologyandToxicityofAntineoplastic Drugs23.Hematopoietic Cell Transplantation24.Treatment of InfectionsinTheImmunocompromisedHost25.AntithromboticTherapy26.Immune Cell Therapy27.VaccineTherapy28.TherapeuticApheresis:Indications,Efficacy,andComplications29.Gene TherapyforHematologicDiseases30.RegenerativeMedicine:MultipotentialCellTherapy forTissueRepairPARTVIThe Erythrocyte31.StructureandCompositionof the Erythrocyte32.Erythropoiesis33.Erythrocyte Turnover34.ClinicalManifestations and Classification ofErythrocyteDisorders35.AplasticAnemia:Acquiredand Inherited.36. Pure Red Cell Aplasia 37. Anemia ofChronicDisease38. The CongenitalDyserythropoieticAnemias39. ParoxysmalNocturnal Hemoglobinuria40. ParoxysmalNocturnalHemoglobinuria41. Folate,Cobalamin,andMegaloblasticAnemias42.IronMetabolism43.Iron Deficiency andOverload44. AnemiaResulting fromOtherNutritionalDeficiencies45. AnemiaAssociatedwithMarrowInfiltration46. Erythrocyte MembraneDisorders47. Erythrocyte Enzyme Disorders48. TheThalassemias:Disorders of GlobinSynthesis49. DisordersofHemoglobinStructure:Sickle CellAnemiaandRelatedAbnormalities50. Methemoglobinemiaand Other Dyshemoglobinemias51. FragmentationHemolyticAnemia52. Erythrocyte Disordersas a ResultofChemicalandPhysicalAgents53. HemolyticAnemiaResultingfromInfectionswithMicroorganisms54. HemolyticAnemiaResultingfromImmuneInjury55. AlloimmuneHemolytic Disease of the FetusandNewborn56. HypersplenismandHyposplenism57. Primary and Secondary Erythrocytoses58.ThePorphyrias59.PolyclonalandHereditarySideroblasticAnemiasPARTVIINeutrophils,Eosinophils,Basophils, and Mast Cells60. StructureandCompositionofNeutrophils,Eosinophils,andBasophils61. Production,Distribution,andFateofNeutrophils62. EosinophilsandRelatedDisorders63. Basophils,Mast Cells, andRelatedDisorders64. ClassificationandClinical ManifestationsofNeutrophilDisorders65. NeutropeniaandNeutrophilia66. DisordersofNeutrophilFunctionPARTVIIIMonocytes and Macrophages67. Structure,Receptors,andFunctionsofMonocytesandMacrophages68. Production,Distribution,andActivationofMonocytesandMacrophages69. ClassificationandClinicalManifestationsof DisordersofMonocytesandMacrophages70. MonocytosisandMonocytopenia71. InflammatoryandMalignantHistiocytosis72. Gaucher Disease andRelatedLysosomalStorageDiseases73. PART IXLymphocytes and Plasma Cells73.TheStructureofLymphocytes andPlasma Cells74.LymphopoiesisFunctionsof B LymphocytesandPlasmaCells inImmunoglobulinProduction75. Functionsof T Lymphocytes:T-CellReceptorsforAntigen76. FunctionsofNaturalKiller Cells77. ClassificationandClinical ManifestationsofLymphocyteandPlasma Cell Disorders79.LymphocytosisandLymphocytopenia80.ImmunodeficiencyDiseases81.HematologicManifestationsofAcquiredImmunodeficiencySyndrome82.MononucleosisSyndromesPART XMalignantMyeloid Diseases83.Classificationand ClinicalManifestationsoftheClonalMyeloidDisorders84.PolycythemiaVera85.EssentialThrombocythemia86.Primary Myelofibrosis87.MyelodysplasticSyndromes88.AcuteMyelogenousLeukemia89.ChronicMyelogenousLeukemiaandRelatedDisordersPART XIMalignantLymphoid Diseases90.ClassificationofMalignantLymphoid Disorders91.AcuteLymphoblasticLeukemia92.ChronicLymphocyticLeukemia93.Hairy Cell Leukemia94.LargeGranularLymphocyticLeukemia95.General ConsiderationsforLymphomas:Epidemiology,Etiology,Heterogeneity,and Primary ExtranodalDisease96.PathologyofLymphomas.97.HodgkinLymphoma98.Diffuse Large B-Cell Lymphoma andRelated Diseases99.FollicularLymphoma100.Mantle Cell Lymphoma101.MarginalZone B-Cell Lymphomas102.BurkittLymphoma103.CutaneousT-CellLymphoma(MycosisFungoidesandSézarySyndrome)104.MatureT-CellandNaturalKiller Cell Lymphomas105.Plasma Cell Neoplasms:General Considerations106.EssentialMonoclonalGammopathy107.Myeloma.108.ImmunoglobulinLight-ChainAmyloidosis109.Macroglobulinemia.110.Heavy-Chain DiseasePART XIIHemostasis andThrombosis111.MegakaryopoiesisandThrombopoiesis112.PlateletMorphology,Biochemistry,and Function113.Molecular Biology andBiochemistryof theCoagulationFactorsandPathwaysofHemostasis114.ControlofCoagulationReactions115.VascularFunction in Hemostasis116.Classification,Clinical Manifestations, andEvaluationofDisordersofHemostasis117.Thrombocytopenia118.Heparin-InducedThrombocytopenia119.ReactiveThrombocytosis120.HereditaryQualitativePlateletDisorders121.AcquiredQualitativePlateletDisorders122.TheVascularPurpuras123. Hemophilia A andHemophilia B124. InheritedDeficiencies ofCoagulation FactorsII,V,V VIII, VII, X, XI, and XII125.Hereditary FibrinogenAbnormalities126.von WillebrandDisease127. Antibody-MediatedCoagulation FactorDeficiencies128. HemostaticAlterations in Liver Disease andLiverTransplantation129. DisseminatedIntravascularCoagulation130.HereditaryThrombophilia131. The AntiphospholipidSyndrome132. ThromboticMicroangiopathies133.VenousThrombosis134. Atherothrombosis: Disease Initiation,Progression,andTreatment135. FibrinolysisandThrombolysisPART XIIITransfusion Medicine136. Erythrocyte AntigensandAntibodies137. Human Leukocyte andPlateletAntigens138. Blood Procurementand Red Cell Transfusion139. Preservationand Clinical UseofPlateletsIndex