This book constitutes the refereed proceedings of the 22nd International Conference on Application and Theory of Petri Nets, ICATPN 2001, held in Newcastle upon Tyne, UK in June 2001. The 19 revised full papers presented together with three invited papers were carefully reviewed and selected from 48 submissions. All current issues on research and development of Petri nets are addressed, in particular timed, stochastic, colored, symmetrical, and high-level Petri nets; formal verification, model checking, embedded systems, real-time systems, dependable computing, and state spaces.